DelveInsight’s, “Dry Eye Disease Pipeline Insight 2023” report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in the Dry Eye Disease pipeline landscape. It covers the Dry Eye Disease pipeline drug profiles, including Dry Eye Disease clinical trials and nonclinical stage products. It also covers the Dry Eye Disease therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To explore more information on the latest breakthroughs in the Dry Eye Disease Pipeline treatment landscape of the report, click here @ Dry Eye Disease Pipeline Outlook
Key Takeaways from the Dry Eye Disease Pipeline Insight Report
For further information, refer to the detailed Dry Eye Disease Unmet Needs, Dry Eye Disease Market Drivers, and Dry Eye Disease Market Barriers, click here for Dry Eye Disease Ongoing Clinical Trial Analysis
Dry Eye Disease Overview
Dry eye disease is defined as a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface. It is accompanied by increased osmolarity of the tear film and subacute inflammation of the ocular surface. Dry eyes can occur when tear production and drainage are not in balance.
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Dry Eye Disease Emerging Drugs Profile
Reproxalap, is a novel small molecule drug candidate for Dry Eye. By inhibiting RASP, which are elevated in a variety of inflammatory diseases, reproxalap represents a novel mechanism for diminishing ocular inflammation in dry eye disease. In a number of clinical trials, reproxalap demonstrated consistent statistically significant and clinically relevant activity. In a Phase II b clinical trial, Aldeyra’s lead RASP inhibitor, reproxalap, demonstrated broad activity across a variety of symptoms and signs in patients with dry eye disease.
RGN-259, a Tβ4-based sterile and preservative-free eye drop, as a novel treatment for dry eye and neurotrophic keratitis (NK). RGN-259 represents a new approach to corneal healing, as there is currently no pharmaceutical agent that has shown corneal repair and anti-inflammatory properties. Preclinical studies have shown that Tβ4 promotes cell migration, increases cell-cell and cell-matrix contacts through increase laminin-5 production, and reduces both apoptosis and inflammation in the cornea.
Visomitin, contains a novel small molecule cardiolipin peroxidation inhibitor, specifically developed to target ophthalmic disorders such as dry eye syndrome, uveitis and age-related macular degeneration, in an eye drop formulation for ease of administration. Visomitin has been developed to deliver a highly active antioxidant, plastoquinone, directly into mitochondria. Visomitin has been shown to accumulate in mitochondria in an extremely targeted and efficient manner. The biochemical characteristics of the mitochondrial membrane and the unique properties of Visomitin direct it into the inner leaflet of the inner mitochondrial membrane with high precision. Once positioned in mitochondria, the molecule acts as a targeted scavenger of reactive oxygen species (ROS) and as a very efficient cardiolipin protector.
Dive deep into rich insights for drugs for Dry Eye Disease Market Drivers and Dry Eye Disease Market Barriers, click here @ Dry Eye Disease Unmet Needs and Analyst Views
Dry Eye Disease Pipeline Therapeutics Assessment
There are approx. 50+ Dry Eye Disease companies which are developing the Dry Eye Disease therapies. The Dry Eye Disease companies which have their Dry Eye Disease drug candidates in the most advanced stage, i.e. phase III include, RegeneRx Biopharmaceuticals.
Scope of the Dry Eye Disease Pipeline Report
Got Queries? Find out the related information on Dry Eye Disease Mergers and acquisitions, Dry Eye Disease Licensing Activities @ Dry Eye Disease Emerging Drugs, and Recent Trends
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